产品货号：
Z15383
中文名称：
DYRK1A抗体
英文名称：
Anti-DYRK1A Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DYRK1A Antibody |
| 指标别名 | Dual specificity tyrosine phosphorylation regulated kinase 1A;DYRK;DYRK1;HP86;MNB;MNBH;MRD7;DYRK1A |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM,ELISA |
| 基因名称 | DYRK1A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human DYRK1A recombinant protein (Position:H38-M269). |
| 实际分子量 | 100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A is an enzyme that in humans is encoded by the DYRK1A gene.This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family.This member contains a nuclear targeting signal sequence,a protein kinase domain,a leucine zipper motif,and a highly conservative 13-consecutive-histidine repeat.It catalyzes its autophosphorylation on serine/threonine and tyrosine residues.It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development.This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene.It is localized in the Down syndrome critical region of chromosome 21,and is considered to be a strong candidate gene for learning defects associated with Down syndrome.Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region.These variants encode at least five different isoforms. |
| Uniprot ID | Q13627 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry in fixed cells 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 |
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